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Related Experiment Videos

Assessing fluid responsiveness during open chest conditions.

D A Reuter1, M S G Goepfert, T Goresch

  • 1Department of Anaesthesiology, University of Munich, 81377 Munich, Germany. Daniel.Reuter@med.uni-muenchen.de

British Journal of Anaesthesia
|December 14, 2004
PubMed
Summary

Ventilation-induced stroke volume variations (SVV) and pulse pressure variations (PPV) effectively assess fluid responsiveness in open-chest cardiac surgery patients. These heart-lung interactions improve hemodynamic management during sternotomy procedures.

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Area of Science:

  • Cardiology
  • Anesthesiology
  • Critical Care Medicine

Background:

  • Optimizing preload is crucial for post-cardiac surgery patients.
  • Ventilation-induced left ventricular stroke volume variations (SVV) and pulse pressure variations (PPV) are established methods for preload optimization.
  • Assessing fluid responsiveness in open-chest conditions during coronary artery bypass surgery requires reliable methods.

Purpose of the Study:

  • To evaluate the efficacy of SVV and PPV, measured via arterial pulse contour analysis, in assessing fluid responsiveness.
  • To determine the utility of these dynamic parameters in patients undergoing coronary artery bypass surgery under open-chest conditions.

Main Methods:

  • The study included 22 patients immediately following midline sternotomy.

Related Experiment Videos

  • SVV, PPV, left ventricular end-diastolic area index (echocardiography), global end-diastolic volume index, and cardiac index (thermodilution) were measured.
  • Measurements were taken before and after blood withdrawal (500 ml) and fluid loading (500 ml hydroxyethyl starch 6%).
  • Main Results:

    • Blood withdrawal significantly increased SVV (6.7% to 12.7%) and PPV (5.2% to 11.9%), while decreasing cardiac index and global end-diastolic volume index.
    • Fluid loading significantly decreased SVV (to 6.8%) and PPV (to 5.4%), increasing cardiac index and global end-diastolic volume index.
    • A significant correlation was found between the increase in cardiac index post-fluid loading and pre-fluid loading SVV (R=0.74) and PPV (R=0.61).

    Conclusions:

    • SVV and PPV measurements reliably assess fluid responsiveness in hypovolemic patients under open-chest and open-pericardium conditions.
    • Monitoring heart-lung interactions using SVV and PPV can enhance hemodynamic management during procedures like mid-line sternotomy.
    • These dynamic indices offer a valuable tool for guiding fluid therapy in specific surgical contexts.