Related Experiment Videos
Diffusion-weighted single shot echo planar imaging of colorectal cancer using a sensitivity-encoding technique
Katsuhiro Nasu1, Yoshihumi Kuroki, Seiko Kuroki
1National Cancer Center Hospital East, Department of Radiology, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan. kanasu@east.ncc.go.jp
Japanese Journal of Clinical Oncology
|December 14, 2004
Summary
Sensitivity-encoding diffusion-weighted imaging (SENSE-DWI) effectively depicts colorectal cancer. This technique offers strong contrast between tumors, normal colon walls, and feces, aiding in diagnosis.
Area of Science:
- Radiology
- Medical Imaging
- Oncology
Background:
- Colorectal cancer diagnosis relies on imaging techniques.
- Diffusion-weighted imaging (DWI) is a valuable tool in MRI.
- Sensitivity encoding (SENSE) can accelerate MRI acquisition.
Purpose of the Study:
- To assess the feasibility of SENSE-DWI for colorectal cancer detection.
- To evaluate the image quality and diagnostic performance of SENSE-DWI.
- To explore the correlation between ADC values and tumor pathology.
Main Methods:
- Forty-two patients with pathologically confirmed sigmoid and rectal cancer underwent T2-TSE and SENSE-DWI.
- SENSE-DWI was performed with b-factors of 0 and 1000 s/mm(2).
- Image analysis included tumor detectability, distortion, misregistration, and ADC measurements.
Main Results:
- SENSE-DWI successfully depicted all colorectal tumors as hyperintense.
- Despite using single-shot EPI, SENSE introduced noticeable image distortion and misregistration.
- High contrast was observed between tumors, normal colon wall, and feces on SENSE-DWI (b=1000 s/mm(2)).
Conclusions:
- SENSE-DWI is a feasible and effective method for visualizing colorectal cancer.
- The technique provides excellent contrast, differentiating tumors from surrounding tissues.
- No significant correlation was found between ADC values and tumor pathological classification.