Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

4.1K
The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
4.1K
Common Ion Effect03:24

Common Ion Effect

47.1K
Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide:
47.1K
What is the Immune System?01:38

What is the Immune System?

132.4K
Overview
132.4K
Variability: Analysis01:11

Variability: Analysis

527
Measures of variability are statistical metrics that reveal the dispersion pattern within a dataset. They are pivotal in biostatistics, providing insights into the heterogeneity within health and biological data. Variability signifies the degree to which data points diverge from one another, helping researchers understand the potential range of values and associated uncertainty within the data.
The range is a simple measure of variability, indicating the difference between the highest and...
527
Random Variables01:09

Random Variables

17.9K
A random variable is a single numerical value that indicates the outcome of a procedure. The concept of random variables is fundamental to the probability theory and was introduced by a Russian mathematician, Pafnuty Chebyshev, in the mid-nineteenth century.
Uppercase letters such as X or Y denote a random variable. Lowercase letters like x or y denote the value of a random variable. If X is a random variable, then X is written in words, and x is given as a number.
For example, let X = the...
17.9K
Associative Learning01:27

Associative Learning

1.5K
Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postnatally acquired cytomegalovirus infection in preterm infants: an update on diagnosis, management and outcomes.

Archives of disease in childhood. Fetal and neonatal edition·2026
Same author

Duration of Postnatal HIV Prophylaxis: How Long Is Long Enough?

The Pediatric infectious disease journal·2026
Same author

Risk factors associated with adverse metabolic health in youth with perinatally acquired HIV living in the United Kingdom.

AIDS (London, England)·2026
Same author

Infants at highest risk of herpes simplex virus disease who should start immediate empiric aciclovir.

Archives of disease in childhood·2026
Same author

Exploring feasibility of clinical psychology as a model of care for families affected by congenital cytomegalovirus.

Journal of pediatric psychology·2026
Same author

Value of targeted testing for cytomegalovirus in preterm infants: 7 years' experience at a tertiary London hospital.

Archives of disease in childhood. Fetal and neonatal edition·2025

Related Experiment Video

Updated: Feb 13, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
05:16

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

3.8K

Recurrent meningitis in association with common variable immune deficiency.

Amitava Pahari1, Cauvery Pal, Hermione Lyall

  • 1Department of Pediatric Infectious Diseases, St Mary's Hospital, Praed Street, London W2 1NY, United Kingdom. apahari@yahoo.com

Indian Pediatrics
|December 14, 2004
PubMed
Summary
This summary is machine-generated.

Recurrent meningitis in children is rare and often linked to underlying issues. This case highlights a connection between recurrent meningitis and Common Variable Immune Deficiency in a pediatric patient.

More Related Videos

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells
09:35

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells

Published on: May 19, 2020

10.9K
Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
07:55

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Published on: August 4, 2011

12.2K

Related Experiment Videos

Last Updated: Feb 13, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
05:16

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

3.8K
Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells
09:35

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells

Published on: May 19, 2020

10.9K
Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
07:55

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Published on: August 4, 2011

12.2K

Area of Science:

  • Pediatric infectious diseases
  • Immunology
  • Neurology

Background:

  • Recurrent meningitis in children is uncommon.
  • Predisposing factors include immune deficiencies and cranio-spinal defects.

Observation:

  • A case of recurrent meningitis in a child is presented.
  • The meningitis was associated with Common Variable Immune Deficiency.

Findings:

  • Common Variable Immune Deficiency (CVID) can manifest with recurrent meningitis in pediatric cases.
  • This association underscores the importance of immunological evaluation in children with unexplained recurrent meningitis.

Implications:

  • Highlights the need for early diagnosis of CVID in children presenting with recurrent meningitis.
  • Suggests that immunological screening should be considered in the workup of recurrent meningitis.
  • Emphasizes the link between primary immunodeficiencies and severe infectious complications like meningitis.