Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Seckel syndrome with polyarteritis nodosa.

Ramazan Kutlu1, Alpay Alkan, Onur Kutlu

  • 1Department of Radiology, Inonu University School of Medicine, Malatya, Turkey. rkutlu@inonu.edu.tr

Indian Pediatrics
|December 14, 2004
PubMed
Summary

Seckel syndrome, a rare genetic disorder, rarely affects the kidneys. This case is the first to report polyarteritis nodosa, a vasculitic disorder, in a child with Seckel syndrome and kidney involvement.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dose-Response and survival analysis after transarterial radioembolization for intrahepatic cholangiocarcinoma: A multicenter multicompartment dosimetry study.

European journal of nuclear medicine and molecular imaging·2026
Same author

Assessing Textbook Oncologic Outcomes in Distal Pancreatectomy for Pancreatic Adenocarcinoma: A National Cancer Database Study.

Journal of clinical medicine·2026
Same author

Lumbar and Thoracolumbar Curves Are Associated with Coronal Lower Limb Malalignment in Adolescent Idiopathic Scoliosis.

Medicina (Kaunas, Lithuania)·2026
Same author

Comparison of Manual Multi-ROI, Single-Location, and Volumetric Fat Fraction Measurements for Hepatic Steatosis Using MRI.

Diagnostics (Basel, Switzerland)·2026
Same author

Pilot evaluation of transcutaneous vagus nerve stimulation in chronic tinnitus: clinical outcomes and DTI insights.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2026
Same author

Evaluation of Humoral and Cellular Immune Responses to the Conjunctival <i>Brucella abortus</i> S19 Vaccine in Türkiye.

Vector borne and zoonotic diseases (Larchmont, N.Y.)·2026

Area of Science:

  • Genetics
  • Nephrology
  • Rheumatology

Background:

  • Seckel syndrome is a rare autosomal recessive disorder characterized by primordial dwarfism and distinctive facial features.
  • Renal involvement is an uncommon manifestation of Seckel syndrome, with limited documented cases.
  • Polyarteritis nodosa is a systemic necrotizing vasculitis primarily affecting medium-sized arteries, often involving the kidneys.

Observation:

  • A 9-year-old boy diagnosed with Seckel syndrome presented with renal complications.
  • Diagnostic evaluation revealed the presence of polyarteritis nodosa as the cause of renal involvement.
  • This clinical presentation is highly unusual, as polyarteritis nodosa has not been previously associated with Seckel syndrome in medical literature.

Findings:

  • This case represents the first documented instance of polyarteritis nodosa occurring in a patient with Seckel syndrome.

Related Experiment Videos

  • The findings highlight a previously unrecognized association between these two rare conditions.
  • The renal involvement in this patient was attributed to the systemic vasculitis of polyarteritis nodosa.

    • Implications:

    • This report expands the spectrum of potential complications associated with Seckel syndrome.
    • It suggests the need for heightened awareness and consideration of vasculitic disorders, such as polyarteritis nodosa, in the differential diagnosis of renal disease in Seckel syndrome patients.
    • Further research may elucidate shared pathophysiological mechanisms or genetic predispositions linking Seckel syndrome and polyarteritis nodosa.