Propofol in the management of postictal delirium with clozapine-electroconvulsive therapy combination
Related Experiment Videos
Pascal Sienaert1, Filip Bouckaert, Isabel Fernandez
1ECT Department, University Center Sint-Jozef, Leuvensesteenweg, Kortenberg, Belgium. pascal.sienaert@uc-kortenberg.be
Abstract:
Postictal delirium is an acute confusional state occurring during the immediate postictal phase in patients receiving electroconvulsive therapy that is characterized by motor agitation, disorientation, clouded consciousness, repetitive stereotyped movements, and poor response to commands. A schizophrenic patient with severe and recurrent postictal delirium is described. The possible role of the clozapine-electroconvulsive therapy combination in the occurrence of postictal delirium is discussed. Several management strategies were tried, with various degrees of success. Propofol proved to be effective in preventing agitation when used as induction agent or when administered at seizure end. However, propofol could not prevent a delirious state when only administered after the first signs of motor restlessness had emerged.
Related Concept Videos
Psychosis: Goals of Pharmacotherapy
Electroconvulsive Therapy
Psychosis and Antipsychotic Drugs: Overview
Mania and Antimanic Drugs: Overview
Drug Therapy
Antianxiety Medications
Antiepileptic Drugs: Potassium Channel Activators
Ezogabine has gained approval as an adjunctive treatment...