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Updated: Aug 20, 2026

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
Published on: September 28, 2022
Severe systemic autoimmune disease associated with Epstein-Barr virus infection
Julián Sevilla1, Maria del Carmen Escudero, Raquel Jiménez
1Pediatric Oncohematology, Hospital Niño Jesús, Menéndez Pelayo 65, Madrid 28009, Spain. jsevilla.hnjs@salud.madrid.org
Abstract:
Infection with Epstein-Barr virus (EBV) has been associated with different autoimmune manifestations. The authors describe a girl who developed a severe systemic autoimmune disease with severe autoimmune hemolytic anemia, mild autoimmune thrombopenia, antineutrophil antibodies, and fatal autoimmune hepatitis after EBV infection. Despite immunosuppressive treatment and ultimately liver transplantation, this patient could not overcome her clinical condition and died. The etiopathogenesis of this complex disease and the association with EBV infection is discussed.
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