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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Herbicidal indolizine-5,8-diones: photosystem I redox mediators
Stephen C Smith1, Eric D Clarke, Stuart M Ridley
1Syngenta, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, United Kingdom. steve.smith@syngenta.com
Abstract:
6,7-Disubstituted indolizine-5,8-diones showed activity as herbicides, giving rapid desiccation symptomology in whole-plant tests and bleaching in leaf-disc assays. In isolated chloroplasts, such compounds initiated rapid uptake of oxygen in Photosystem I. A redox mediator mode of action was further supported by electrochemical studies. Several compounds described had low photostability, high volatility, hydrolytic instability or reactivity with glutathione. The detrimental effects that these factors may have had on expression of herbicidal activity are discussed.
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