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Related Experiment Videos

Postexercise left ventricular function and cTnT in recreational marathon runners.

Keith George1, Gregory Whyte, Claire Stephenson

  • 1Research Institute for Sport and Exercise Science, Henry Cotton Campus, Liverpool John Moores University, Liverpool, United Kingdom. k.george@livjm.ac.uk

Medicine and Science in Sports and Exercise
|December 15, 2004
PubMed
Summary

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Prolonged exercise in athletes did not impair left ventricular (LV) systolic function. However, cardiac troponin T (cTnT) levels increased, and diastolic function (E:A ratio) decreased, with unclear causes.

Area of Science:

  • Cardiology
  • Exercise Physiology
  • Sports Medicine

Background:

  • Endurance exercise can impact cardiac function.
  • Cardiac troponin T (cTnT) elevation post-exercise is observed but not fully understood.
  • Left ventricular (LV) function assessment is crucial in athletes undergoing prolonged physical stress.

Purpose of the Study:

  • To evaluate the effects of prolonged exercise on LV function.
  • To investigate the appearance of cTnT in athletes after endurance events.
  • To correlate these changes with exercise duration and physiological parameters.

Main Methods:

  • 35 recreational athletes underwent pre- and post-race assessments.
  • Echocardiography measured LV function parameters (SV, EF, E:A ratio, LVIDd, wall stress).

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  • Heart rate, blood pressure, and cTnT levels were recorded; in-event data was also collected.

    • Main Results:

    • Stroke volume (SV) and LV internal dimension at end-diastole (LVIDd) decreased significantly post-race.
    • Ejection fraction (EF) and LV wall stress remained unchanged.
    • Diastolic filling (E:A ratio) decreased significantly, and cTnT levels were elevated in most subjects post-race.

    Conclusions:

    • No evidence of impaired LV systolic function was found.
    • Post-exercise cTnT elevation and reduced E:A ratio were observed but not directly linked to LV systolic function or exercise parameters.
    • The etiology of cTnT changes and altered diastolic function remains uncertain.