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A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
Indications for and long-term survival in patients with automatic implantable cardioverter-defibrillators
Wilbert S Aronow1, Carmine Sorbera, Anil Chagarlamudi
1From the Department of Medicine, Cardiology Division, Westchester Medical Center/New York Medical College, Valhalla, New York.
Insights
Automatic implantable cardioverter-defibrillators (AICDs) show good survival rates across various patient groups. These devices offer significant long-term benefits for individuals at risk of sudden cardiac death.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Sudden cardiac death (SCD) remains a significant cause of mortality.
- Automatic implantable cardioverter-defibrillators (AICDs) are crucial in preventing SCD.
- Patient selection for AICD implantation is based on various risk factors and underlying cardiac conditions.
Purpose of the Study:
- To evaluate the long-term survival rates of patients implanted with AICDs.
- To assess the efficacy of AICDs in different patient cohorts defined by the indication for implantation.
- To provide real-world data on AICD outcomes in a diverse patient population.
Main Methods:
- A retrospective analysis of 473 patients (378 men, 95 women) who received AICD implantation.
- Patients were categorized based on the primary indication for AICD: cardiac arrest due to ventricular fibrillation/tachycardia, spontaneous sustained ventricular tachycardia with structural heart disease, syncope with inducible ventricular arrhythmias, or nonsustained ventricular tachycardia with coronary artery disease and inducible arrhythmias.
- Survival data was collected at a mean follow-up of 3.6 years.
Main Results:
- Overall survival at 3.6 years was 85% for all 473 patients.
- Survival rates varied by indication: 76% for cardiac arrest, 85% for spontaneous sustained VT with structural heart disease, 92% for syncope with inducible VT/VF, and 84% for nonsustained VT with CAD and inducible VT/VF.
- The study included patients with a mean age of 69 +/- 12 years.
Conclusions:
- AICD implantation is associated with favorable long-term survival across a spectrum of cardiac conditions.
- The effectiveness of AICDs is demonstrated in patients with high risk for sudden cardiac death, including those with ventricular arrhythmias.
- These findings support the continued use of AICDs for primary and secondary prevention of sudden cardiac death in appropriate patient populations.
Abstract:
Automatic implantable cardioverter-defibrillators (AICDs) were implanted in 378 men and 95 women, mean age 69 +/- 12 years. At 3.6-year follow up, survival was 76% in patients who had an AICD because of cardiac arrest as a result of ventricular fibrillation or ventricular tachycardia not resulting from a transient or reversible cause; 85% in patients who had an AICD because of spontaneous sustained ventricular tachycardia in association with structural heart disease; 92% in patients who had an AICD because of syncope of undetermined origin with clinically relevant, hemodynamically sustained ventricular tachycardia or ventricular fibrillation induced at electrophysiological study when drug therapy is ineffective, not tolerated, or not preferred; 84% in patients who had an AICD because of nonsustained ventricular tachycardia with coronary artery disease, prior myocardial infarction, left ventricular dysfunction, and inducible ventricular fibrillation or sustained ventricular tachycardia at electrophysiological study that is not suppressible by a class I antiarrhythmic drug; and 85% in all 473 patients who had an AICD.
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