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[Modification of blood viscosity and elasticity. Principle therapeutic approach in relation to its pathophysiology]
P Költringer1, W Langsteger, P Lind
1Abteilung für Neurologie und Psychiatrie, Krankenhaus der Barmherzigen Brüder Graz-Eggenberg.
Exercising a therapeutic influence on the viscoelastic properties of whole blood is a very complex matter. In general, apart from hemodilution, the modification of such factors as erythrocyte aggregation, red cell rigidity or plasma viscosity, all of which may be influenced more or less independently of one another, are possible approaches. The present article discusses the basic possibilities of influencing the viscoelasticity of blood for therapeutic purposes, with attention being paid in particular to the pathogenesis of hyperviscosemia.
Exercising a therapeutic influence on the viscoelastic properties of whole blood is a very complex matter. In general, apart from hemodilution, the modification of such factors as erythrocyte aggregation, red cell rigidity or plasma viscosity, all of which may be influenced more or less independently of one another, are possible approaches. The present article discusses the basic possibilities of influencing the viscoelasticity of blood for therapeutic purposes, with attention being paid in particular to the pathogenesis of hyperviscosemia.