Related Experiment Video
Updated: Aug 20, 2026
Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
Published on: April 3, 2016
A randomized trial of the effects of rigid contact lenses on myopia progression
Jeffrey J Walline1, Lisa A Jones, Donald O Mutti
1The Ohio State University College of Optometry, Columbus 43210-1240, USA. walline.1@osu.edu
Objective:
To compare the effects of rigid gas-permeable contact lenses (RGPs) and soft contact lenses (SCLs) on myopia progression in children.
Methods:
We randomly assigned 116 subjects to wear RGPs or SCLs. Subjects underwent cycloplegic autorefraction, keratometry, and A-scan ultrasonographic axial length measurements at each annual visit. All analyses were conducted according to the original randomization assignment. The primary outcome measure was the 3-year change in spherical equivalent cycloplegic autorefraction.
Results:
The mean +/- SD spherical equivalent cycloplegic refractive error progressed -1.56 +/- 0.95 diopters (D) for RGP wearers and -2.19 +/- 0.89 D for the SCL wearers during the 3 years of the study (analysis of covariance [ANCOVA], P<.001). The axial growth of the eyes was not significantly different between treatment groups (ANCOVA, P = .57). The steep corneal meridian of the RGP wearers steepened 0.62 +/- 0.60 D, and that of the SCL wearers steepened 0.88 +/- 0.57 D during the 3 years (ANCOVA, P = .01).
Conclusions:
The RGP wearers' myopia progressed less than that of the SCL wearers. The corneal curvature of the SCL wearers steepened more than that of the RGP wearers, but the axial growth was not significantly different between the groups. Most refractive error treatment effect was limited to the first year of the trial. The results of the study provide information for eye care practitioners to share with their patients, but they do not indicate that RGPs should be prescribed primarily for myopia control.
