Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Randomised controlled trials (RCTs) to evaluate complex healthcare interventions--a case study.

Ian Chi Kei Wong1,

  • 1Centre for Paediatric Pharmacy Research, The School of Pharmacy, University of London, London WC1N 1AX, UK. ian.wong@ulsop.ac.uk

Pharmacy World & Science : PWS
|December 16, 2004
PubMed
Summary

This study evaluated community-based pharmaceutical care for older adults, applying a framework for complex interventions. Researchers detailed the research process, from conception to piloting and modification, offering insights for pharmacy practice studies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Artificial Intelligence for Evidence Synthesis of Emerging Biologics to Improve Skeletal Health in Osteogenesis Imperfecta: Systematic Review and Meta-Analysis.

Journal of medical Internet research·2026
Same author

Prenatal Acetaminophen (Paracetamol) Use and the Risk of Autism and/or Attention-Deficit/Hyperactivity Disorder Among Sibling-Matched Cohorts.

JAMA internal medicine·2026
Same author

Association of Reduction in Continuity of Care During COVID-19 Pandemic With Cardiovascular Diseases, Kidney Failure and All-Cause Mortality for People With Diabetes: A Cohort Study in Hong Kong.

Diabetes, obesity & metabolism·2026
Same author

Authors' reply: Myasthenia gravis following the initiation of statin therapy.

Journal of internal medicine·2026
Same author

The optimal blood pressure target in old and very old patients with hypertension.

Age and ageing·2026
Same author

Optimal blood pressure target in patients with uncomplicated hypertension: a target trial emulation study.

Nature communications·2026

Area of Science:

  • Pharmacy practice research
  • Health services research
  • Geriatric pharmacotherapy

Background:

  • The UK National Health Service (NHS) identified older adults as a vulnerable group requiring significant pharmaceutical intervention in 2001.
  • The National Service Framework for the Elderly (NSF-E) promoted 'medicines management' and 'pharmaceutical care' in community settings for elderly patients.
  • A multidisciplinary research team designed a project to evaluate community-based pharmaceutical care for the elderly, funded by the Medical Research Council (MRC).

Purpose of the Study:

  • To describe the application of the MRC's framework for complex interventions in a large randomized trial of pharmaceutical care for the elderly.
  • To detail the research process, including planning, implementation, and modifications after piloting.
  • To share challenges encountered, such as patient confidentiality issues, and their resolutions, for the benefit of other pharmacy practice researchers.

Related Experiment Videos

Main Methods:

  • Application of the Medical Research Council's (MRC) framework for complex interventions.
  • Design and execution of a large randomized trial evaluating community-based pharmaceutical care.
  • Systematic documentation of research stages: idea generation, planning, implementation, piloting, and modification.

Main Results:

  • The study successfully applied a framework for complex interventions to a large-scale randomized trial.
  • The research process, from inception through piloting and modification, was documented.
  • Practical challenges, including patient confidentiality, were identified and resolved.

Conclusions:

  • The described research process and problem-solving offer valuable insights for future pharmacy practice research, particularly in geriatric care.
  • The study demonstrates the feasibility of applying the MRC's complex interventions framework to pharmaceutical care research.
  • Effective medicines management and pharmaceutical care are crucial for the elderly population.