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Updated: Aug 20, 2026

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
Published on: November 23, 2019
Imaging knee position using MRI, RSA/CT and 3D digitisation
A McPherson1, J Kärrholm, V Pinskerova
1Centre For Biomedical Engineering, UCL (RNOHT) London, UK. andy@kneemotion.org
Abstract:
The purpose of this study was to compare 3 methods of imaging knee position. Three fresh cadaver knees were imaged at 6 flexion angles between 0 degrees and 120 degrees by MRI, a combination of RSA and CT and 3D digitisation (in two knees). Virtual models of all 42 positions were created using suitable computer software. Each virtual model was aligned to a newly defined anatomically based Cartesian coordinate system. The angular rotations around the 3 coordinate system axes were calculated directly from the aligned virtual models using rigid body kinematics and found to be equally accurate for the 3 methods. The 3 rotations in each knee could be depicted using anatomy-based diagrams for all 3 methods. We conclude that the 3 methods of data acquisition are equally and adequately accurate in vitro. MRI may be the most useful in vivo.