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Related Experiment Videos

Muscle carnitine after strenuous endurance exercise.

J Decombaz1, B Gmuender, G Sierro

  • 1Nestec Limited, Research Centre, Vers-chez-les-Blanc, Lausanne, Switzerland.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|February 1, 1992
PubMed
Summary

Very long endurance exercise significantly decreased free carnitine and increased short-chain acylcarnitine in athletes. However, trained individuals with moderate carnitine intake are unlikely to develop carnitine deficiency from strenuous aerobic exercise.

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Area of Science:

  • Exercise Physiology
  • Nutritional Biochemistry

Background:

  • Carnitine plays a crucial role in energy metabolism, particularly during prolonged exercise.
  • Understanding carnitine's response to extreme endurance events is vital for athletes and sports scientists.

Purpose of the Study:

  • To investigate the impact of a very long endurance exercise event on muscle carnitine levels in cross-country skiers.
  • To determine if strenuous aerobic exercise leads to carnitine deficiency in trained athletes.

Main Methods:

  • Eighteen cross-country skiers participated in a 13.5-hour Alpine race.
  • Muscle carnitine concentrations (total, free, and acylcarnitine) were measured before and after the exercise.
  • Dietary carnitine intake was assessed for two weeks prior to the event.

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Main Results:

  • Total muscle carnitine remained unchanged after the race.
  • A significant 20% decrease in muscle free carnitine was observed post-exercise.
  • A significant 108% increase in muscle short-chain acylcarnitine occurred after the endurance event.
  • Interindividual differences in baseline muscle carnitine were consistent and not correlated with dietary intake.

Conclusions:

  • Strenuous aerobic exercise, even of extreme duration, does not appear to cause carnitine deficiency in trained athletes consuming a moderate carnitine diet.
  • The observed changes in free and acylcarnitine suggest a shift in muscle energy metabolism during prolonged exercise.