Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiac changes during behavioral stress in dogs.

R A Galosy, L K Clarke, J H Mitchell

    The American Journal of Physiology
    |May 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Evaluation of reduced-tillering (tin) wheat lines in managed, terminal water deficit environments.

    Journal of experimental botany·2013
    Same author

    A case for diagnosis (acrodermatitis?).

    Archives of dermatology and syphilology·2010
    Same author

    A method of approach to psychosomatic problems in allergy.

    The West Virginia medical journal·2010
    Same author

    Congenital cutaneous atrophy on hands and shins; recent dysphagia.

    Archives of dermatology and syphilology·2010
    Same author

    Asphyxia following Dental Extraction in a Haemophiliac.

    British medical journal·2010
    Same author

    Some psychosomatic aspects of allergic diseases.

    Psychosomatic medicine·2010

    Controlled behavioral stress significantly increased cardiac performance in dogs, enhancing heart rate and left ventricular function without increasing physical activity. This study reveals stress impacts on cardiovascular regulation.

    Area of Science:

    • Cardiovascular Physiology
    • Behavioral Stress Research
    • Animal Models in Cardiology

    Background:

    • Understanding the physiological impact of stress on the cardiovascular system is crucial.
    • Behavioral stressors can elicit significant physiological responses.
    • Previous research has explored stress-induced changes in heart rate and blood pressure.

    Purpose of the Study:

    • To investigate the effects of controlled behavioral stress on cardiac function in dogs.
    • To differentiate between phasic and tonic changes in cardiovascular parameters during stress.
    • To compare the cardiac responses of stressed animals to a nonstressed control group.

    Main Methods:

    • Utilized a Sidman avoidance task as a controlled behavioral stressor in chronically instrumented dogs.

    Related Experiment Videos

  • Monitored heart rate (HR), left ventricular systolic pressure (LVP), and maximum rate of left ventricular pressure development (LV dP/dtmax).
  • Compared cardiovascular measurements in an experimental group (n=4) with a nonstressed control group (n=4) over 13 days.

    • Main Results:

    • Experimental dogs exhibited both phasic and tonic increases in HR, LVP, and LV dP/dtmax during the stress paradigm.
    • Left ventricular systolic pressure showed reduced sensitivity to stress over time, returning to baseline by day 13.
    • Nonstressed controls displayed decreases in cardiac function when alterations were observed, contrasting with the stressed group.

    Conclusions:

    • Controlled behavioral stress enhances cardiac performance without a corresponding increase in overall bodily activity.
    • Hypothesized that pre-avoidance heart rate increases are vagally mediated, while avoidance-related increases involve beta-sympathetic activity and vascular adaptations.
    • Suggests distinct neural and hormonal mechanisms underlie cardiac responses to different phases of behavioral stress.