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Aortoiliac thrombosis in antiphospholipid syndrome-case report and literature review

Jesús M Alfayate1, Francisco Acín, Alicia Bueno

  • 1Angiology and Vascular Surgery, University Hospital, Getafe, Madrid, Spain.

Vascular and Endovascular Surgery
|December 16, 2004
PubMed

Insights

Antiphospholipid syndrome causes hypercoagulability, leading to early thrombotic events, primarily in leg veins and the brain. This case highlights rare aortic occlusion as a potential complication of antiphospholipid syndrome.

Area of Science:

  • Cardiovascular Medicine
  • Hematology
  • Autoimmune Diseases

Background:

  • Antiphospholipid syndrome (APS) is a significant cause of hypercoagulable states, particularly in women.
  • Thrombotic events in APS often occur at a younger age compared to atherosclerotic disease.
  • Venous thrombosis predominantly affects lower limbs, while arterial events are common in the cerebral territory.

Observation:

  • Aortic disease is infrequently reported in patients with APS.
  • This report details a rare case of infrarenal aortic occlusion.
  • The occlusion extended to involve both iliac arteries in a patient with primary APS.

Findings:

  • The presented case demonstrates a severe manifestation of APS-related vascular disease.
  • Infrarenal aortic and iliac artery occlusion is a rare but possible complication of primary antiphospholipid syndrome.
  • This finding expands the spectrum of thrombotic events associated with APS.

Implications:

  • Highlights the need for vigilance regarding potential aortic complications in APS patients.
  • Suggests that comprehensive vascular assessment may be warranted in select APS cases.
  • Contributes to understanding the diverse clinical manifestations of antiphospholipid syndrome.

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