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Related Experiment Videos

Invasive aspergillosis with polyarthritis.

S F Mekan1, O Saeed, J A Khan

  • 1Department of Biological and Biomedical Sciences, The Aga Khan University Hospital, Karachi, Pakistan. sabeenmekan@hotmail.com

Mycoses
|December 17, 2004
PubMed
Summary

A rare case of Aspergillus fumigatus caused septic arthritis in an 18-year-old male

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Area of Science:

  • Infectious Diseases
  • Rheumatology
  • Mycology

Background:

  • Septic arthritis typically presents with bacterial pathogens.
  • Fungal arthritis is uncommon, especially in immunocompetent individuals.
  • Aspergillus fumigatus is a known opportunistic pathogen.

Observation:

  • An 18-year-old male presented with low-grade fever and polyarticular joint involvement.
  • Affected joints included knees, ankles, and metacarpophalangeal joints.
  • Skin and joint lesions were biopsied and cultured.

Findings:

  • Diagnosis confirmed Aspergillus fumigigatus as the causative agent.
  • The patient's symptoms resolved with itraconazole treatment.
  • This highlights a rare presentation of invasive fungal infection.

Implications:

  • Clinicians should consider fungal etiology in unexplained chronic arthritis.
  • Prompt diagnosis and antifungal therapy are crucial for favorable outcomes.
  • This case expands the spectrum of Aspergillus-related joint infections.

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