Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Skeletal muscle tissue engineering.

A D Bach1, J P Beier, J Stern-Staeter

  • 1Department of Plastic and Hand Surgery, University of Erlangen Medical Centre, Erlangen, D-91054, Germany. Alexander.Bach@chir.imed.uni-erlangen.de

Journal of Cellular and Molecular Medicine
|December 17, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reconstruction of hip flexion after arthroscopic iliopsoas tendon release using free functional muscle.

JPRAS open·2025
Same author

Intraoperative Assessment of Nerve Traction Injury in Obstetric Brachial Plexus Palsy.

Journal of brachial plexus and peripheral nerve injury·2025
Same author

[Microsurgery].

Operative Orthopadie und Traumatologie·2024
Same author

Comparison of adipose derived stromal cells cultured on fibroin scaffolds fabricated by salt-leaching and by freeze-thawing.

Biomaterials advances·2024
Same author

Anconeus epitrochlearis muscle (epitrochlearisanconeus muscle; Musculus epitrochleoanconeus) with cubital tunnel syndrome - a rare but relevant clinical entity.

Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft·2023
Same author

Editorial: Interdisciplinary surgical strategies for complex tumor defects in modern oncology.

Frontiers in oncology·2023
Same journal

Valsartan Reduces Myocardial Ischemia-Reperfusion Injury by Inhibiting Ferritinophagy-Mediated Ferroptosis.

Journal of cellular and molecular medicine·2026
Same journal

Metabolic Dysregulation of FC3 Fibrochondrocytes via MDH2 Promotes Intervertebral Disc Degeneration.

Journal of cellular and molecular medicine·2026
Same journal

PGK1 Drives Glial Glycolytic Reprogramming to Mediate Isoflurane-Induced Cognitive Impairment in Aged Mice.

Journal of cellular and molecular medicine·2026
Same journal

Oxypaeoniflorin Ameliorates Titanium Particle-Stimulated Osteolysis by Targeting Nrf2 to Reprogram Mitochondrial Homeostasis in Osteoclasts.

Journal of cellular and molecular medicine·2026
Same journal

Correction to 'TLR4 Contributes to the Damage of Cartilage and Subchondral Bone in Discectomy-Induced TMJOA Mice'.

Journal of cellular and molecular medicine·2026
Same journal

EXPRESSION OF CONCERN: An Upstream Open Reading Frame Regulates Vasculogenic Mimicry of Glioma via ZNRD1-AS1/miR-499a-5p/ELF1/EMI1 Pathway.

Journal of cellular and molecular medicine·2026
See all related articles

Tissue engineering offers a promising alternative for regenerating functional skeletal muscle lost to injury or disease. While challenges remain, recent scientific advancements are paving the way for new therapeutic strategies.

Area of Science:

  • Regenerative Medicine
  • Biomedical Engineering
  • Musculoskeletal Research

Background:

  • Skeletal muscle loss due to trauma, tumor ablation, or myopathies presents a significant reconstructive challenge.
  • Current surgical methods like transplantation and transposition offer limited functional restoration.
  • The development of functional skeletal muscle substitutes remains a critical unmet need in regenerative medicine.

Purpose of the Study:

  • To review recent advancements in skeletal muscle tissue engineering.
  • To explore novel approaches for creating and regenerating functional skeletal muscle tissue.
  • To highlight the potential of tissue engineering in addressing muscle defects.

Main Methods:

  • Review of current literature on skeletal muscle tissue engineering.

Related Experiment Videos

  • Analysis of recent findings in biomaterials, cell therapies, and bioreactor technologies for muscle regeneration.
  • Synthesis of data on in vitro and in vivo studies of engineered muscle constructs.

    • Main Results:

    • Tissue engineering strategies are advancing, showing potential for functional muscle regeneration.
    • Recent research focuses on optimizing scaffold design, cell sourcing, and mechanical stimulation.
    • Despite progress, achieving full functional integration and long-term viability of engineered muscle remains a challenge.

    Conclusions:

    • Skeletal muscle tissue engineering is a rapidly evolving field with significant therapeutic potential.
    • Continued research is crucial to overcome existing hurdles and translate engineered muscle into clinical practice.
    • This field offers a promising avenue for restoring function in patients with muscle loss or damage.