Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Major genes affecting ovulation rate in sheep.

George Henry Davis1

  • 1AgResearch, Invermay Agricultural Centre, Private Bag, Mosgiel, New Zealand. george.davis@agresearch.co.nz

Genetics, Selection, Evolution : GSE
|December 17, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

Genomic dissection of hoof and leg conformation in Swiss dairy cattle populations reveals polygenic architecture and a recessive HYAL1 nonsense variant affecting longevity in Holstein cattle.

Genetics, selection, evolution : GSE·2026
Same journal

The mitogenome diversity of Alpine Rendena cattle: new clues on its maternal origin and the complex substructure of haplogroup T3.

Genetics, selection, evolution : GSE·2026
Same journal

Genomic partitioning and functional dissection of inbreeding depression for stature in Brown Swiss cattle.

Genetics, selection, evolution : GSE·2026
Same journal

Modest contribution of metabolomic data to genomic prediction of breeding values for feed conversion ratio in pigs.

Genetics, selection, evolution : GSE·2026
Same journal

Determining crossover count and position in two pig lines with different selection histories.

Genetics, selection, evolution : GSE·2026
Same journal

Effect of methylation on genome mutability in cattle.

Genetics, selection, evolution : GSE·2026

Major genes significantly boost sheep prolificacy and reproductive performance. DNA testing identifies mutations in genes like BMPR-1B, BMP15, and GDF9, enabling genetic improvement programs for increased ovulation rates.

Area of Science:

  • Animal Genetics
  • Reproductive Biology
  • Sheep Breeding

Background:

  • Research since 1980 highlights major genes' potential to increase sheep prolificacy.
  • Identified mutations in BMPR-1B, BMP15, and GDF9 genes influence ovulation rates.

Purpose of the Study:

  • To review the inheritance patterns and DNA testing of major prolificacy genes in sheep.
  • To assess the impact of specific gene mutations on ovulation rate and reproductive performance.

Main Methods:

  • Analysis of inheritance patterns for prolificacy genes.
  • Identification and characterization of mutations in BMPR-1B, BMP15, and GDF9.
  • Review of DNA testing services for marker-assisted selection.

Main Results:

Related Experiment Videos

  • Mutations in BMPR-1B, BMP15, and GDF9 genes increase ovulation rates in sheep.
  • Different inheritance modes (autosomal, X-linked) and effects (dominant, over-dominant) observed.
  • Mutation effects range from 0.4 to 1.5 extra ovulations per oestrus.

Conclusions:

  • Major genes offer significant potential for improving sheep reproductive performance globally.
  • Commercial DNA testing facilitates the use of these genes in genetic improvement programs.
  • Understanding gene inheritance is crucial for effective marker-assisted selection in sheep breeding.