Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Delayed post-anoxic leukoencephalopathy].

L Peter1, N Nighoghossian, A Jouvet

  • 1Service d'Urgences Neurovasculaires, Hôpital Neurologique, Lyon.

Revue Neurologique
|December 17, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A new anti-outer plexiform layer antibody in autoimmune retinopathy?

Journal francais d'ophtalmologie·2025
Same author

History and novelties in autoimmune encephalitis and paraneoplastic neurological syndromes.

Revue neurologique·2024
Same author

Mechanisms of immune tolerance breakdown in paraneoplastic neurological syndromes.

Revue neurologique·2024
Same author

Safety and efficacy of reperfusion therapies in acute ischemic stroke related to left ventricular thrombus: A retrospective cohort study.

Revue neurologique·2024
Same author

Autonomic nervous system involvement in autoimmune encephalitis and paraneoplastic neurological syndromes.

Revue neurologique·2023
Same author

A novel peptide derived from vascular endothelial growth factor prevents amyloid beta aggregation and toxicity.

Aging cell·2023
Same journal

Macrophage inclusions in patients undergoing antisense oligonucleotide therapy for ALS or SMA: A retrospective and transversal study.

Revue neurologique·2026
Same journal

Geographic disparities in MRI features of ischemic stroke and small vessel disease: A comparative study between French Guiana and mainland France. Findings from the BECATOUR multicenter registry.

Revue neurologique·2026
Same journal

Continuous subcutaneous perfusion of apomorphine in Parkinson's disease: Towards monotherapy?

Revue neurologique·2026
Same journal

Neuro-Whipple presenting as autoimmune encephalitis.

Revue neurologique·2026
Same journal

Multimodal assessment of minimally conscious state and cognitive motor dissociation in neurocritical care: A critical review.

Revue neurologique·2026
Same journal

Development of a new episodic memory assessment tool (NEM): Preliminary data and clinical perspectives.

Revue neurologique·2026
See all related articles

Delayed post-anoxic encephalopathy can manifest weeks after hypoxic injury. This case highlights a patient with delayed neurological symptoms and white matter demyelination following benzodiazepine overdose.

Area of Science:

  • Neurology
  • Neuroscience
  • Pathology

Background:

  • Post-anoxic encephalopathies can present with delayed onset after initial hypoxic injury.
  • Hypoxic events, such as drug overdose, can precipitate delayed neurological complications.

Observation:

  • A 45-year-old woman developed confusional state, akinetic mutism, and parkinsonism three weeks after benzodiazepine ingestion.
  • Neuroimaging revealed bilateral hemispheric white matter and globus pallidus abnormalities.
  • EEG showed diffuse slow activity, and investigations for leukodystrophies were negative.

Findings:

  • Brain biopsy confirmed widespread demyelination with axonal sparing in the white matter.
  • The clinical presentation and investigations were consistent with delayed post-anoxic leukoencephalopathy.

Related Experiment Videos

Implications:

  • This case underscores the importance of considering delayed post-anoxic leukoencephalopathy in patients with unexplained neurological deterioration after hypoxia.
  • Early recognition and diagnosis are crucial for appropriate patient management and potential recovery.