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Updated: Aug 14, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Tuberculous osteomyelitis of the knee
A Combalia1, S Sastre, P Esteban
1Department of Orthopaedic Surgery and Pathology, Muskuloskeletal Oncology Unit, Hospital Clinic, C/Villarroel 170, 08036 Barcelona, Spain.
Abstract:
Tuberculosis is a mycobacterial infestation which generally involves the lungs. Primary bone tuberculosis without involving the joint is rare. A 35-year-old Pakistani immigrant presented with a mass and pain over the medial aspect of the knee that had persisted for 6 months. Clinical and radiological investigations revealed a tuberculous affectation of the distal epiphysis of the femur. We did not find any visceral organ involvement. Wide excision was performed, completed with antituberculostatic drugs for 9 months postoperatively. In the 2nd postoperative year, the patient was symptom-free, and the imaging test results were normal. Primary bone tuberculosis without joint affection is a rare presentation form of this disease and should be kept in mind in the diagnostic work-up of a mass of a bone lesion.
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