Angina pectoris: a review of current and emerging therapies

John O Parker1

  • 1Department of Medicine, Queen's University.

Insights

Angina pectoris, a symptom of ischemic heart disease, affects millions. While treatments exist, revascularization surgeries are increasing, prompting exploration of novel therapies like spinal cord stimulation and gene therapy.

Area of Science:

  • Cardiology
  • Ischemic Heart Disease Management

Background:

  • Angina pectoris is a significant symptom of ischemic heart disease, impacting millions in the US.
  • Current pharmacologic treatments are insufficient, as evidenced by rising revascularization surgery rates.

Purpose of the Study:

  • To review current and emerging management strategies for angina pectoris.
  • To highlight alternative and advanced therapies beyond traditional treatments.

Main Methods:

  • Literature review of existing pharmacologic treatments.
  • Exploration of novel management strategies including device-based and genetic therapies.

Main Results:

  • Despite available medications, revascularization surgeries are on the rise.
  • Several innovative treatments are under investigation for refractory angina.

Conclusions:

  • There is a growing need for effective angina management strategies.
  • Emerging therapies like spinal cord stimulation and gene therapy show promise for ischemic heart disease.

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