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Invasive meningococcal disease presenting as Henoch-Schonlein purpura
M N Tsolia1, A Fretzayas, H Georgouli
1Second Department of Pediatrics, Athens University School of Medicine, P. and A. Kyriakou Children's Hospital, 115 27 Athens, Greece. matsolia@ath.forthnet.gr
Summary
Henoch-Schonlein purpura (HSP) can be triggered by infections. Two children with invasive meningococcal disease showed HSP symptoms, suggesting a link between meningococcal infection and HSP.
Area of Science:
- Pediatrics
- Infectious Diseases
- Rheumatology
Background:
- Henoch-Schonlein purpura (HSP) is a common childhood vasculitis.
- HSP is often preceded by infections, typically viral or bacterial.
- The exact triggers for HSP are not always identified.
Observation:
- Two pediatric cases of invasive meningococcal disease are presented.
- Both children exhibited clinical and laboratory findings characteristic of HSP.
- The presentation mimicked typical Henoch-Schonlein purpura.
Findings:
- Invasive meningococcal disease was diagnosed in both patients.
- The patients presented with symptoms consistent with Henoch-Schonlein purpura.
- This suggests a potential causal relationship.
Implications:
- Meningococcal infections should be considered as a potential trigger for HSP.
- Early recognition of this association may aid in diagnosis and management.
- Further research is warranted to confirm the link between meningococcal disease and HSP.