Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nailfold video-capillaroscopy in systemic sclerosis.

M Cutolo1, C Pizzorni, A Sulli

  • 1Department of Internal Medicine, University of Genova, Viale Benedetto xv,6, 16132 Genova, Italy. mcutolo@unige.it

Zeitschrift Fur Rheumatologie
|December 18, 2004
PubMed
Summary

Raynaud's phenomenon (RP) is a common condition indicating microvascular issues. Nailfold capillary microscopy effectively differentiates primary RP from secondary RP associated with rheumatic diseases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nailfold capillaroscopy and organ involvement in systemic sclerosis: a systematic review.

Best practice & research. Clinical rheumatology·2026
Same author

Capillaroscopy in the daily clinic of the pediatric rheumatologist.

Best practice & research. Clinical rheumatology·2024
Same author

Consensus statement on the diagnosis and treatment of sclerosing diseases of the skin, Part 1: Localized scleroderma, systemic sclerosis and overlap syndromes.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

An engineered glove to follow finger function in rheumatoid arthritis: an observational prospective study.

Rheumatology international·2023
Same author

Emerging nailfold capillaroscopic patterns in COVID-19: from acute patients to survivors.

Reumatismo·2023
Same author

Nailfold capillaroscopy in the rheumatological current clinical practice in Italy: results of a national survey.

Reumatismo·2022

Area of Science:

  • Rheumatology
  • Vascular Biology
  • Diagnostic Imaging

Background:

  • Raynaud's phenomenon (RP) is a prevalent clinical condition necessitating prompt microvascular assessment.
  • Microvascular involvement is central to RP, often co-occurring with various rheumatic diseases.

Purpose of the Study:

  • To highlight the utility of nailfold capillary microscopy in evaluating microvascular changes associated with Raynaud's phenomenon.
  • To differentiate primary RP from secondary RP linked to systemic rheumatic diseases.

Main Methods:

  • Nailfold capillary microscopy (NVC) was employed as a non-invasive, cost-effective diagnostic tool.
  • Videocapillaroscopic patterns were analyzed, particularly in patients with scleroderma (SSc).

Main Results:

Related Experiment Videos

  • Scleroderma-associated NVC patterns reveal structural capillary damage, including giant capillaries and microhemorrhages, and reduced capillary density.
  • NVC facilitates early differentiation between primary (functional) and secondary (disease-associated) RP.
  • Distinct NVC patterns are observed across different rheumatic diseases, correlating with clinical symptoms, disease severity, and laboratory findings.

Conclusions:

  • Nailfold capillary microscopy is a valuable, cost-effective method for assessing microvascular involvement in Raynaud's phenomenon.
  • NVC aids in the early diagnosis and differentiation of primary versus secondary RP, especially in the context of rheumatic diseases.
  • Further research is needed for standardized, computerized quantification of microvascular damage observed via NVC.