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The investigation of perivasculary space under the myocardial bridge in different species
1Veterinary Faculty, Department of Anatomy, Dicle University, Diyarbakir, Turkey.
Abstract:
Our purpose in this study was to investigate the perivasculary space under the myocardial bridges (MB) in dog, sheep, goat and human hearts. A total of 160 hearts were studied, and perivasculary space under the myocardial bridges was examined under microscope. The specimens belonged to 25 dogs, 100 sheep, 25 goats and 10 humans. Special attention was paid to evaluate the distance between the MB and coronary arteries (CA), CA and underlying myocardium (UM) and to find the relation of concomitant vein number accompanying the CA and MB. 219 myocardial bridges were found in total of hearts, and specimens from these bridges were examined under microscope. There were large variations in distance between the MB and CA (0-714 microm) and distance between CA and UM (0-309 microm). The myocardial bridges were classified into three groups in terms of the number of veins accompanying CA, the bridges with no concomitant veins with one concomitant vein and with two concomitant veins. This suggests that the distance between the MB and CA is crucial to determine how much force is on the CA. The environment surrounding the CA may be a crucial factor in determining whether the MB influences the induction of heart disorders or not.
Insights
Investigating the perivascular space beneath myocardial bridges (MB) in various species revealed crucial distances between MB and coronary arteries (CA). These distances, along with vein presence, may influence heart disorder induction.
Area of Science:
- Cardiovascular Anatomy
- Comparative Pathology
Background:
- Myocardial bridges (MB) are congenital anomalies where a segment of a coronary artery (CA) runs through the heart muscle.
- The perivascular space surrounding CAs under MBs is a critical anatomical region influencing CA mechanics.
Purpose of the Study:
- To investigate the anatomical characteristics of the perivascular space beneath myocardial bridges.
- To evaluate the relationship between myocardial bridges, coronary arteries, and surrounding structures in multiple species.
Main Methods:
- Microscopic examination of 160 hearts from dogs, sheep, goats, and humans.
- Quantification of distances between myocardial bridges (MB) and coronary arteries (CA), and CA and underlying myocardium (UM).
- Classification of MBs based on the number of accompanying veins.
Main Results:
- 219 myocardial bridges were identified across all specimens.
- Significant variations in the distance between MB and CA (0-714 micrometers) and CA and UM (0-309 micrometers) were observed.
- MBs were categorized into three groups based on the presence of zero, one, or two concomitant veins.
Conclusions:
- The distance between the myocardial bridge and the coronary artery is a key determinant of the mechanical forces exerted on the artery.
- The perivascular environment surrounding the coronary artery is a critical factor in MBs' potential role in inducing cardiac disorders.