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Disseminated tuberculosis complicating anti-TNF-alpha treatment
K Dimakou1, D Papaioannides, P Latsi
1Department of Respiratory Medicine, University of Athens Medical School, Sotiria Hospital, Athens, Greece.
International Journal of Clinical Practice
|December 21, 2004
Abstract:
An unusually large number of cases of tuberculosis, often of miliary or disseminated form, have been reported in patients receiving infliximab therapy for rheumatoid arthritis or Crohn's disease. We describe a patient with rheumatoid arthritis who was treated with infliximab and became systemically ill with Mycobacterium tuberculosis-disseminated infection. Patients who are candidates for treatment with tumour necrosis factor-alfa inhibitors should be evaluated for the presence of latent or active