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Analog CMOS circuit design and characterization for optical coherence tomography signal processing
Rajesh Kariya1, David L Mathine, Jennifer K Barton
1Electrical and Computer Engineering Department, University of Arizona, Tucson, AZ 85721, USA. rajesh@ece.arizona.edu
IEEE Transactions on Bio-Medical Engineering
|December 21, 2004
Summary
Researchers created a custom analog circuit for optical coherence tomography (OCT) signal processing. This novel circuit effectively processes Doppler frequencies to generate clear OCT images, demonstrated by imaging an onion.
Area of Science:
- Biomedical Engineering
- Electrical Engineering
- Optical Imaging
Background:
- Optical Coherence Tomography (OCT) is a powerful non-invasive imaging technique.
- Efficient signal processing is crucial for high-resolution OCT.
- Existing OCT systems may benefit from optimized analog circuitry for specific applications.
Purpose of the Study:
- To develop and validate a custom analog CMOS circuit for OCT signal processing.
- To extract Doppler frequency and generate filtered A-scans.
- To demonstrate the circuit's capability in producing 2D OCT images.
Main Methods:
- Designed a custom analog CMOS circuit using 1.5 microm low-noise technology.
- Implemented Doppler frequency extraction and electrical mixing.
- Utilized the circuit for signal processing in an OCT system.
- Acquired a two-dimensional image of an onion.
Main Results:
- Successfully developed a functional analog CMOS circuit for OCT signal processing.
- The circuit effectively extracts Doppler frequencies.
- Filtered A-scans were generated by electrically mixing the Doppler frequency with the original signal.
- A clear two-dimensional image of an onion was produced.
Conclusions:
- The custom analog CMOS circuit is a viable solution for OCT signal processing.
- This approach simplifies and potentially enhances OCT imaging systems.
- The demonstrated imaging of an onion validates the circuit's performance.