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Updated: Aug 20, 2026
Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins
Published on: August 31, 2019
[Determination of entrapment efficiency of breviscapine nanoliposomes]
Fei Xiong1, Jia-bi Zhu, Wei Wang
1Institute of Pharmaceutics, China Pharmaceutical University, Nanjing 210009, China.
Aim:
To determine the entrapment efficiency of breviscapine nanoliposomes.
Methods:
Retrodialysis method was used to determine the entrapment efficiency of breviscapine nanoliposomes. The drug recovery and the sample recovery were considered to verify the feasibility of the method.
Results:
The drug recovery was (99.6 +/- 0.6)%. The sample recovery was (99.9 +/- 0.8)%. The entrapment efficiency of breviscapine nanoliposomes was (75.3 +/- 2.3)%.
Conclusion:
The method used in this study is simple, applicable and accurate for determination of the entrapment efficiency of breviscapine nanoliposomes.
