Related Experiment Video
Updated: Aug 20, 2026

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
Published on: May 9, 2025
Antiviral therapy with non-selective beta-blockers: preliminary experimental and clinical corroboration
1karin@swissmail.com
Abstract:
Treatment with non-selective beta-blockers has been proposed to have an indirect antiviral activity acting via an enhanced performance of the immune system, and the mechanism of this activity has been laid out earlier. Experimental and clinical findings are presented that corroborate the hypothesis that inhibiting the immunosuppressive and stress-related cAMP-PKA pathway will enhance the immune system's ability to recognize foreign antigen and to access its vast repertory in an improved way, resulting in an indirect antiviral activity. Other drugs having an inhibitory effect on the cAMP-PKA pathway in cells of the immune system and therefore expected to have a comparable activity spectrum with different specific side-effects are presented, for example aspirin. Additionally the so far unexplained anticancer activity of aspirin is related to the same mechanism of an enhanced performance of the immune system.
Related Concept Videos
Antihypertensive Drugs: Types of β-Blockers
Adrenergic Antagonists: Chemistry and Classification of β-Receptor Blockers
Adrenergic Antagonists: Pharmacological Actions of β-Receptor Blockers
Adrenergic Antagonists: ɑ and β-Receptor Blockers
Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers
Antihypertensive Drugs: Action of β1 Blockers

