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Updated: May 10, 2026

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy
Published on: June 8, 2018
Around the world of DNA damage INO80 days
1Howard Hughes Medical Institute and Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Abstract:
DNA damage is detected and repaired in the context of chromatin. In this issue of Cell, van Attikum et al. (2004) and Morrison et al. (2004) demonstrate that double-stranded break repair involves the recruitment of a specialized chromatin remodeling complex, INO80, through an interaction with phosphorylated histone H2A.
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