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Updated: Aug 8, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
LiveBench-8: the large-scale, continuous assessment of automated protein structure prediction
Leszek Rychlewski1, Daniel Fischer
1BioInfoBank Institute, Limanowskiego 24A/16, 60-744 Poznan, Poland.
Abstract:
We present the results of the evaluation of the latest LiveBench-8 experiment. These results provide a snapshot view of the state of the art in automated protein structure prediction, just before the 2004 CAFASP-4/CASP-6 experiments begin. The last CAFASP/CASP experiments demonstrated that automated meta-predictors entail a significant advance in the field, already challenging most human expert predictors. LiveBench-8 corroborates the superior performance of meta-predictors, which are able to produce useful predictions for over one-half of the test targets. More importantly, LiveBench-8 identifies a handful of recently developed autonomous (nonmeta) servers that perform at the very top, suggesting that further progress in the individual methods has recently been obtained.
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