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The EMBL Nucleotide Sequence Database.

Carola Kanz1, Philippe Aldebert, Nicola Althorpe

  • 1EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. ckanz@ebi.ac.uk

Nucleic Acids Research
|December 21, 2004
PubMed
Summary

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This summary is machine-generated.

The EMBL Nucleotide Sequence Database offers a vast collection of genetic sequences and annotations. Recent updates enhance data accessibility and quality for researchers worldwide.

Area of Science:

  • Bioinformatics
  • Genomics
  • Molecular Biology

Background:

  • The EMBL Nucleotide Sequence Database is a key resource for genetic information.
  • It is maintained by the European Bioinformatics Institute (EBI) and collaborates internationally with DDBJ and GenBank.
  • Daily data exchange ensures synchrony among collaborating institutes.

Purpose of the Study:

  • To provide a comprehensive and up-to-date collection of nucleotide sequences and annotations.
  • To facilitate data submission and access for researchers.
  • To integrate nucleotide data with other molecular biology resources.

Main Methods:

  • Utilizes Webin for individual sequence submissions, including Third Party Annotation (TPA) and alignments.
  • Employs automated procedures for large-scale sequencing projects and patent office data.

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  • Provides access via FTP and WWW interfaces, including the Sequence Retrieval System (SRS).

    • Main Results:

    • Daily distribution of new and updated data records.
    • Full database releases occur four times annually.
    • Enhanced functionality includes removal of sequence length limits and the EMBLCDSs dataset.

    Conclusions:

    • The EMBL Nucleotide Sequence Database is a vital, evolving resource for the scientific community.
    • Continuous updates and improved accessibility support genomic research.
    • International collaboration ensures a synchronized and comprehensive global nucleotide sequence repository.