Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

VFDB: a reference database for bacterial virulence factors.

Lihong Chen1, Jian Yang, Jun Yu

  • 1State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100052, China.

Nucleic Acids Research
|December 21, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Glassy dynamics and mechanical response in dense fluids of soft repulsive spheres. I. Activated relaxation, kinetic vitrification, and fragility.

The Journal of chemical physics·2011
Same author

Climatic reconstruction at the Miocene Shanwang basin, China, using leaf margin analysis, CLAMP, coexistence approach, and overlapping distribution analysis.

American journal of botany·2011
Same author

Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning.

Endocrine-related cancer·2011
Same author

Stress and strain analysis of contractions during ramp distension in partially obstructed guinea pig jejunal segments.

Journal of biomechanics·2011
Same author

Role of Gα(12)- and Gα(13)-protein subunit linkage of D(3) dopamine receptors in the natriuretic effect of D(3) dopamine receptor in kidney.

Hypertension research : official journal of the Japanese Society of Hypertension·2011
Same author

Transarticular screw and C1 hook fixation for os odontoideum with atlantoaxial dislocation.

World neurosurgery·2011
Same journal

Neurochondrin promotes U5 snRNP maturation by regulating AAR2 release from PRPF8.

Nucleic acids research·2026
Same journal

Elongationless start-stop elements are stress-resilient translation gates that are more repressive than uTranslons.

Nucleic acids research·2026
Same journal

Evolution of the ribosomal exit tunnel through the eyes of the nascent chain.

Nucleic acids research·2026
Same journal

Enhancing the performance and interpretability of epigenetic clocks.

Nucleic acids research·2026
Same journal

FABIAN-variant 2026: improved prediction of the effects of DNA variants on transcription factor binding.

Nucleic acids research·2026
Same journal

Structural and biochemical characterization of Grimontia hollisae thermostable direct hemolysin with DNA reveals first Vibrio hemolysin with nuclease activity.

Nucleic acids research·2026
See all related articles

The Virulence Factor Database (VFDB) centralizes information on bacterial virulence factors (VFs) to aid researchers in understanding and combating infectious diseases. This comprehensive resource supports scientific discovery in microbial pathogenesis.

Area of Science:

  • Microbiology
  • Pathogenesis
  • Bioinformatics

Background:

  • Bacterial pathogens pose a significant global public health threat.
  • Research has advanced understanding of molecular mechanisms in bacterial pathogenesis.
  • A centralized resource for bacterial virulence factors (VFs) is needed to support future studies.

Purpose of the Study:

  • To establish a comprehensive and user-friendly database of virulence factors (VFs) from medically significant bacterial pathogens.
  • To provide scientists with a unified platform for accessing, searching, and retrieving VF information.

Main Methods:

  • Development of the Virulence Factor Database (VFDB) at http://www.mgc.ac.cn/VFs/
  • Implementation of search functionalities including browsing by genus and keyword search.

Related Experiment Videos

  • Integration of a BLAST search tool for VF-related genes.

    • Main Results:

    • VFDB offers a centralized repository for VF data.
    • The database is designed for ease of use, allowing efficient information retrieval.
    • VFDB facilitates data storage, searching, retrieval, and updates.

    Conclusions:

    • VFDB serves as a crucial resource for researchers studying bacterial pathogenesis.
    • The database enhances accessibility to knowledge on bacterial VFs.
    • VFDB supports ongoing efforts to combat infectious diseases caused by bacterial pathogens.