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Related Experiment Videos

CYGD: the Comprehensive Yeast Genome Database.

U Güldener1, M Münsterkötter, G Kastenmüller

  • 1Institute for Bioinformatics, GSF National Research Center for Environment and Health, Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany.

Nucleic Acids Research
|December 21, 2004
PubMed
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The Comprehensive Yeast Genome Database (CYGD) offers extensive data on yeast Saccharomyces cerevisiae cellular functions and interactions. It aids in annotating new yeast genomes by using S. cerevisiae as a reference.

Area of Science:

  • Molecular Biology
  • Genomics
  • Bioinformatics

Background:

  • Saccharomyces cerevisiae is a key eukaryotic model organism.
  • Comprehensive data on yeast cellular functions and interactions is crucial for biological research.
  • Existing resources may lack integrated information on functional networks and comparative genomics.

Purpose of the Study:

  • To create a centralized data resource for yeast (Saccharomyces cerevisiae) cellular functions.
  • To integrate information on gene/protein functions, physical and functional interactions, and cellular networks.
  • To facilitate the annotation of newly sequenced yeast genomes using S. cerevisiae as a reference.

Main Methods:

  • Compilation of data from various sources on Saccharomyces cerevisiae.

Related Experiment Videos

  • Integration of information on protein-protein interactions, metabolic pathways, and regulatory networks.
  • Development of tools for comparative genomics, including the Similarity Matrix of Proteins (SIMAP).

    • Main Results:

    • The Comprehensive Yeast Genome Database (CYGD) provides extensive information on yeast gene and protein functions.
    • CYGD includes data on physical and functional interactions, forming cellular networks (pathways, signal transduction, gene clusters).
    • The database facilitates exploration of related yeast genomes using S. cerevisiae as a reference backbone.

    Conclusions:

    • CYGD serves as a valuable, integrated resource for yeast research.
    • The database enhances the annotation process for newly sequenced yeast genomes.
    • CYGD supports systems biology approaches by providing insights into yeast cellular networks.