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The UCSC Proteome Browser.

Fan Hsu1, Tom H Pringle, Robert M Kuhn

  • 1Center for Biomolecular Science and Engineering, School of Engineering, University of California Santa Cruz (UCSC), Santa Cruz, CA 95064, USA. fanhsu@soe.ucsc.edu

Nucleic Acids Research
|December 21, 2004
PubMed
Summary
This summary is machine-generated.

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The UCSC Proteome Browser integrates genomic and proteomic data, offering simultaneous access to both. This tool provides comprehensive protein information and links to diverse biological databases for enhanced research.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics and Proteomics

Background:

  • The University of California Santa Cruz (UCSC) Proteome Browser offers extensive protein data.
  • It is integrated with the UCSC Genome Browser, linking genomic and proteomic information.

Purpose of the Study:

  • To provide researchers with simultaneous access to both genome and proteome data.
  • To present a wealth of protein information through graphical displays and external links.

Main Methods:

  • The Proteome Browser displays tracks for protein and genomic sequences, exon structure, and various protein properties.
  • It visualizes genome-wide distributions of protein characteristics using histograms.
  • Data is linked to external resources like InterPro, Pfam, KEGG, and the Protein Data Bank.

Related Experiment Videos

Main Results:

  • Users can simultaneously view genomic and proteomic data.
  • The browser displays detailed protein features including domains, sequence properties, and potential modifications.
  • Genome-wide histograms illustrate the distribution of protein properties.

Conclusions:

  • The UCSC Proteome Browser provides an integrated platform for exploring genomic and proteomic data.
  • It enhances research by linking diverse biological databases and presenting comprehensive protein information.
  • Available for human, mouse, and rat, it offers a valuable resource for the scientific community.