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[Dermatological disease among HIV-infected patients with CD4-lymphocyte count]

Lessandra Michelim1, José Luiz Atti, Daniel Panarotto

  • 1Serviço de Controle de Infecção Hospitalar, Hospital Geral de Caxias do Sul, RS, Brazil.

Revista De Saude Publica
|December 21, 2004
PubMed

Insights

Dermatological diseases are common in HIV-infected patients. Lower CD4-lymphocyte counts correlate with a higher prevalence and number of skin conditions, indicating disease progression.

Area of Science:

  • Immunology
  • Dermatology
  • Infectious Diseases

Context:

  • Human Immunodeficiency Virus (HIV) infection significantly impacts immune function.
  • Dermatological manifestations are common in HIV-infected individuals.
  • CD4-lymphocyte count is a key indicator of immune status in HIV patients.

Purpose:

  • To investigate the correlation between the prevalence of dermatological diseases and CD4-lymphocyte counts in HIV-infected patients.
  • To analyze the relationship between immune status and skin conditions in this population.

Summary:

  • A case series study analyzed 238 HIV-infected patients (198 hospitalized, 40 outpatients) in Brazil.
  • High prevalence of dermatological diseases (67.2% hospitalized, 75.0% outpatients) was observed, with oral candidiasis being most frequent.
  • Lower CD4 counts were significantly associated with the presence and number of dermatological diseases in both patient groups (p<0.05).

Impact:

  • Findings highlight the strong link between immune suppression and skin disease in HIV.
  • This correlation can aid in monitoring disease progression and immune status.
  • Understanding this relationship is crucial for managing HIV-infected patients effectively.
Abstract

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