Related Experiment Video
Updated: Aug 20, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
Asthma and other allergic conditions in Colombia: a study in 6 cities
Rodolfo Dennis1, Luis Caraballo, Elizabeth García
1Clinical Epidemiology and Biostatistics Unit, Pontificia Universidad Javeriana, Bogotá, Colombia.
Insights
Allergic diseases like asthma and rhinitis are prevalent in Colombian children and adults, causing significant lost school and workdays. This study highlights the substantial burden of these conditions in urban Colombia.
Area of Science:
- Epidemiology
- Public Health
- Immunology
Background:
- Limited data exists on the prevalence and impact of allergic diseases in Colombia and Latin America.
- Allergic diseases affect both children and adults, necessitating a comprehensive understanding of their burden.
Purpose of the Study:
- To determine the prevalence of asthma, allergic rhinitis, and atopic dermatitis symptoms in six Colombian cities.
- To assess patient costs, school and workdays lost, and disease severity.
- To measure total and specific IgE levels in subjects with asthma.
Main Methods:
- A multistage stratified random sampling method was employed, including children aged 5-18, and adults and younger children through systematic sampling.
- Home visits were conducted for data collection.
- Blood samples were collected from subjects experiencing asthma symptoms.
Main Results:
- The study surveyed 6,507 individuals.
- Past 12-month prevalence was 10.4% for asthma, 22.6% for rhinitis, and 3.9% for atopic dermatitis.
- Asthma was associated with emergency visits/hospitalization (38%), lost school/workdays (50%), and high atopy rates (76%).
Conclusions:
- Allergic diseases represent a significant public health concern in urban Colombia.
- The societal impact, including economic costs and lost productivity, is substantial.
- These findings challenge the misconception that allergic diseases are solely a concern for industrialized nations.
Background:
No detailed information is available on the burden and impact of allergic diseases simultaneously for adults and children in Colombia and most Latin American countries.
Objectives:
To investigate the prevalence of asthma, allergic rhinitis, and atopic dermatitis symptoms in 6 cities in Colombia; to measure patient expenses and school days and workdays lost; to describe disease severity; and to determine levels of total and specific IgE in asthmatic subjects.
Methods:
A multistage stratified random sample selection of schools with subjects aged 5 to 18 years in each city was used. Guardian subjects selected were contacted, and home visits were arranged. Subjects aged 1 to 4 years and older than 19 years were also selected randomly by systematic sampling based on the addresses of the subjects aged 5 to 18 years. Subjects with asthma symptoms were invited to provide a blood sample.
Results:
Information was obtained from 6,507 subjects. The prevalence of asthma, rhinitis, and atopic dermatitis symptoms in the past 12 months was 10.4% (95% confidence interval [CI], 9.7%-11.1%), 22.6% (95% CI, 21.6%-23.6%), and 3.9% (95% CI, 3.4%-4.4%), respectively. Thirty-eight percent of asthmatic subjects had visited the emergency department or have been hospitalized, and 50% reported lost school days and workdays. Seventy-six percent of sampled asthmatic patients were considered to be atopic.
Conclusions:
The burden of disease and societal consequences of allergic entities in urban settings in countries such as Colombia are of concern but are largely ignored, perhaps because of the misconception that these diseases are of public health importance only in industrialized nations.
More Related Videos
Related Concept Videos
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Asthma I: Introduction
Asthma-I: Introduction
Asthma III: Clinical Manifestations
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Antiasthma Drugs: β2-Adrenoceptor Agonists
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce relaxation in these...
