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Reflectance pulse oximetry in fetal lambs
A C Dassel1, R Graaff, J G Aarnoudse
1Department of Obstetrics and Gynecology, University Hospital Groningen, The Netherlands.
Pediatric Research
|March 1, 1992
Summary
A new reflectance pulse oximeter was developed for fetal monitoring and low perfusion states. This device accurately measures arterial oxygen saturation using reflected light, overcoming limitations of transmission pulse oximetry.
Area of Science:
- Biomedical Engineering
- Physiological Measurement
- Neonatal Monitoring
Background:
- Transmission pulse oximetry is standard but fails in fetal monitoring and low perfusion.
- Limitations necessitate alternative methods for accurate arterial oxygen saturation measurement.
Purpose of the Study:
- To develop and evaluate a novel reflectance pulse oximeter for measuring arterial oxygen saturation.
- To assess its performance in fetal lambs under varying oxygen saturation levels.
Main Methods:
- Developed a reflectance pulse oximeter utilizing the red/infrared ratio of reflected light.
- Conducted acute experiments on fetal lambs, varying inspired oxygen to achieve saturation levels of 17-82%.
- Calibrated the device against fetal arterial blood samples, using linear regression analysis.
Main Results:
- Established a calibration curve: red/infrared ratio = 4.088 - (0.038 * SaO2), with r = 0.96.
- Demonstrated a precision of 4.7% oxygen saturation.
- Achieved a 95% confidence interval of +/- 9.4% for measurements.
Conclusions:
- The developed reflectance pulse oximeter is a viable alternative for arterial oxygen saturation monitoring.
- It shows promise for clinical applications where transmission pulse oximetry is inadequate, such as fetal monitoring.