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Related Experiment Videos

Optic Nerve Sheath Meningiomas.

Sunita Radhakrishnan1, Michael S Lee

  • 1Cole Eye Institute, Desk I-32, Cleveland Clinic Foundation, Cleveland, OH 44124, USA.

Current Treatment Options in Neurology
|December 22, 2004
PubMed
Summary

Observation is recommended for optic nerve sheath meningiomas (ONSMs) with preserved vision. Treatment, including fractionated radiation, is reserved for declining vision or intracranial extension, aiming to preserve or improve visual function.

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Area of Science:

  • Neuro-oncology
  • Ophthalmology
  • Radiation Oncology

Background:

  • Optic nerve sheath meningiomas (ONSMs) are slow-growing tumors.
  • Untreated ONSMs can maintain visual function for years.
  • Treatment risks vision loss, making observation a viable option.

Purpose of the Study:

  • To outline the management strategy for ONSMs.
  • To detail treatment options and indications for ONSMs.
  • To emphasize the importance of visual function monitoring.

Main Methods:

  • Observation with regular follow-up (4-6 months initially, then annually).
  • Neuroimaging for tumor size assessment.
  • Fractionated radiation therapy (stereotactic or 3D conformal) for progressive disease or intracranial extension.

Main Results:

  • Observation preserves visual function in many ONSM patients.
  • Fractionated radiation can improve or stabilize vision.
  • Surgical resection is reserved for specific cases with high risk of vision loss.

Conclusions:

  • Observation is the preferred approach for ONSMs with stable visual function.
  • Fractionated radiation is the primary treatment for symptomatic or progressing ONSMs.
  • Surgical intervention is considered for extensive intracranial tumors or blind eyes.

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