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Nutritional support in patients with inflammatory bowel disease
C C Lowen1, L M Greene, S A McClave
1Department of Medicine, University of Louisville School of Medicine, KY 40292.
Postgraduate Medicine
|April 1, 1992
Summary
Total parenteral nutrition (TPN) for inflammatory bowel disease (IBD) offers short-term benefits. Total enteral nutrition (TEN) provides similar success, is cost-effective, and supports gut health for better symptom management.
Area of Science:
- Gastroenterology
- Clinical Nutrition
- Inflammatory Bowel Disease (IBD) Management
Background:
- Total parenteral nutrition (TPN) with bowel rest is a traditional therapy for reducing inflammatory bowel disease (IBD) activity and inducing remission.
- However, the positive effects of TPN are often transient.
Purpose of the Study:
- To compare the efficacy and benefits of total enteral nutrition (TEN) versus TPN in managing IBD.
- To highlight the advantages of TEN in terms of cost, gut integrity, and symptom control.
Main Methods:
- Review of existing literature comparing TPN and TEN for IBD treatment.
- Analysis of outcomes related to disease activity, remission rates, cost-effectiveness, and gut health maintenance.
Main Results:
- Total enteral nutrition (TEN) achieves similar remission rates to TPN in IBD patients.
- TEN is more cost-effective than TPN.
- TEN supports gut integrity, stimulates immunocompetence, and aids in symptom and disease activity control.
Conclusions:
- Enteral nutrition is a viable and often preferable alternative to parenteral nutrition for IBD management.
- The use of specialized enteral formulas is expected to increase.
- Dietary modifications, including restrictions on fat, fiber, lactose, or oxalate, may be necessary for individual IBD patients to alleviate symptoms and prevent complications.