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A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
Published on: November 3, 2016
The causal pathway model and cerebral palsy
Harold C Griffin1, Christine L Fitch, Linda W Griffin
1Department of Special Education, College of Education, East Carolina University, Greenville, NC 27858, USA. griffinh@mail.ecu.edu
Insights
This review examines prenatal, perinatal, and postnatal factors contributing to cerebral palsy (CP). It evaluates how these causes interact and presents interventions based on a causal pathway model for CP.
Area of Science:
- Neurology
- Developmental Pediatrics
- Public Health
Background:
- Cerebral palsy (CP) is a complex neurological disorder affecting movement and posture.
- Understanding the multifactorial etiology of CP is crucial for effective prevention and management.
- Existing literature often examines etiological factors in isolation.
Purpose of the Study:
- To comprehensively review prenatal, perinatal, and postnatal causes of cerebral palsy.
- To analyze the interactive effects of identified etiological factors.
- To propose intervention strategies aligned with a causal pathway model of CP.
Main Methods:
- Systematic literature review of studies on cerebral palsy etiology.
- Analysis of interactive effects between different causal factors.
- Development of an intervention framework based on a causal pathway model.
Main Results:
- Identified key prenatal, perinatal, and postnatal risk factors for CP.
- Highlighted the synergistic impact of multiple etiological contributors.
- Grouped potential interventions according to their position in the causal pathway.
Conclusions:
- Cerebral palsy arises from a complex interplay of factors across the prenatal, perinatal, and postnatal periods.
- A causal pathway model provides a framework for understanding these interactions.
- Targeted interventions, informed by this model, are essential for mitigating CP risk and impact.
Abstract:
This article reviews possible prenatal, perinatal, and postnatal causes of cerebral palsy. The interactive effects of various causes are evaluated. Groups of intervention strategies are then presented based on the causal pathway model.
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