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Updated: Aug 20, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Usefulness of four prognostic indices in differentiated thyroid cancer
Fernando Bolaños-Gil-de-Montes1, Manuel González-Ortiz, Gonzalo Vázquez-Camacho
1Department of Endocrinology, Western National Medical Center, Mexican Institute of Social Security, Guadalajara, Jal. Mexico.
Objective:
To report the follow up of 82 patients with differentiated thyroid cancer in order to evaluate patients' clinical and tumor characteristics of prognostic value.
Patients And Methods:
A prospective and comparative study was performed in 82 patients with differentiated thyroid cancer followed for a mean of 84 months. They were classified and included into four prognostic indices (pTNM, DeGroot's, AGES and NTCTCS) stages I and II were considered as a low risk ones and stages III and IV as a high risk group. At the end of the follow up period the patients were evaluated and divided into two groups, those with tumor activity (persistence or recurrence) and those in remission. A correlation coefficient and concordance analysis between the prognostic indices was done. Sensitivity, specificity and positive and negative predictive values were calculated in accordance with the tumor activity or the remission status.
Results:
The highest correlation coefficient (r = 0.91, CI 0.85 to 0.94) was found between NTCTCS and pTNM indexes. The highest sensitivity (78%) and specificity (85.7%) was obtained with the NTCTCS index.
Conclusion:
In our population, NTCTCS index was a good option to evaluate the prognosis of patients with differentiated thyroid cancer.