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COPD in Japan: the Nippon COPD Epidemiology study
Yoshinosuke Fukuchi1, Masaharu Nishimura, Masakazu Ichinose
1Department of Respiratory Medicine, Juntendo University, Tokyo, Japan. yfukuchi@med.juntendo.ac.jp
Summary
The Nippon COPD Epidemiology (NICE) Study found a 10.9% prevalence of airflow limitation in Japanese adults, indicating under-recognized Chronic Obstructive Pulmonary Disease (COPD). Enhanced screening and interventions are crucial due to high smoking rates and an aging population.
Area of Science:
- Pulmonology
- Epidemiology
- Public Health
Background:
- Chronic Obstructive Pulmonary Disease (COPD) prevalence is understudied in Asia.
- High smoking rates in Japan necessitate understanding COPD prevalence.
- The Nippon COPD Epidemiology (NICE) Study addresses this knowledge gap.
Purpose of the Study:
- To measure the prevalence of airflow limitation in Japanese adults.
- To identify risk factors associated with airflow limitation.
- To assess the current recognition of COPD in Japan.
Main Methods:
- Spirometry was used to define airflow limitation based on Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria (FEV1/FVC < 70%).
- Data on clinical factors, spirometry, and risk factors were collected from 2343 Japanese adults aged 40 years and older.
- The study population was designed to be demographically representative of Japan.
Main Results:
- The prevalence of airflow limitation was 10.9% in Japanese adults aged 40 and over.
- Airflow limitation was significantly more common in males (16.4%) than females (5.0%), and increased with age.
- A substantial proportion of airflow limitation cases (90.6%) were undiagnosed, including cases in non-smokers and individuals under 60.
Conclusions:
- The prevalence of airflow limitation in Japan is higher than previously estimated, indicating significant under-diagnosis of COPD.
- The combination of high smoking prevalence and an aging demographic poses a growing challenge for COPD.
- There is an urgent need for improved screening, prevention, and treatment strategies for COPD in Japan.