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GMD@CSB.DB: the Golm Metabolome Database.

Joachim Kopka1, Nicolas Schauer, Stephan Krueger

  • 1Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476 Golm, Germany.

Bioinformatics (Oxford, England)
|December 23, 2004
PubMed
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The Golm Metabolome Database (GMD) provides open access to mass spectral libraries and metabolite profiling data. This platform facilitates global collaboration to advance metabolomics research and metabolite identification.

Area of Science:

  • Metabolomics
  • Systems Biology
  • Functional Genomics

Background:

  • Metabolite profiling using gas chromatography-mass spectrometry (GC-MS) is crucial for systems biology and functional genomics.
  • Applications include drug discovery, herbicide action studies, and understanding gene expression effects on metabolism.
  • The need for accessible data mirrors that of transcript and protein information.

Purpose of the Study:

  • To present The Golm Metabolome Database (GMD) as an open access resource.
  • To facilitate the unambiguous identification of metabolites in complex biological samples.
  • To establish a platform for the open exchange of metabolomics data and bioinformatics tools.

Main Methods:

  • Development of an open access metabolome database (GMD).

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  • Provision of public access to custom mass spectral libraries.
  • Inclusion of metabolite profiling experiments, methods, spectral information, and compound data.

    • Main Results:

    • GMD offers public access to a comprehensive collection of mass spectra for metabolite identification.
    • The database serves as a central hub for experimental research and bioinformatics in metabolomics.
    • It supports multidisciplinary cooperation for the advancement of metabolomics.

    Conclusions:

    • GMD enhances the accessibility of metabolomics data, crucial for research in functional genomics and systems biology.
    • The database promotes collaborative efforts in metabolite identification and data sharing.
    • GMD is a valuable resource for laboratories worldwide, supporting biotechnological applications and drug discovery.