Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gene-environment interactions: implications for sudden unexpected deaths in infancy.

C E Hunt1

  • 1National Center on Sleep Disorders Research, National Heart, Lung, and Blood Institute, NIH, One Rockledge Centre, Room 6022, 6705 Rockledge Drive, 7993, Bethesda, MD 20892-7993, USA. huntc@nhlbi.nih.gov

Archives of Disease in Childhood
|December 23, 2004
PubMed
Summary

Sudden Infant Death Syndrome (SIDS) arises from complex gene-environment interactions. Understanding these genetic and environmental factors is crucial for advancing SIDS research and prevention strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inpatient comparison of wireless and wired pulse oximetry in neonates.

Journal of neonatal-perinatal medicine·2022
Same author

Caffeine decreases intermittent hypoxia in preterm infants nearing term-equivalent age.

Journal of perinatology : official journal of the California Perinatal Association·2017
Same author

The clinical utility of anthropometric measures to assess adiposity in a cohort of prematurely born infants: Correlations with MRI fat quantification.

Journal of neonatal-perinatal medicine·2017
Same author

Anthropometric trends from 1997 to 2012 in infants born at ⩽28 weeks' gestation or less.

Journal of perinatology : official journal of the California Perinatal Association·2017
Same author

Meet the National Center on Sleep Disorders Research and the National Heart, Lung, and Blood Institute: research opportunities in sleep medicine.

Sleep & breathing = Schlaf & Atmung·2002
Same author

Relationship between infant sleep position and motor development in preterm infants.

Journal of developmental and behavioral pediatrics : JDBP·2001

Area of Science:

  • Systems biology
  • Molecular genetics
  • Genetics and environment interactions

Background:

  • Genes and proteins form complex networks influencing biological life.
  • Sudden Infant Death Syndrome (SIDS) is a complex condition.
  • Recent advances in molecular genetics offer new insights into SIDS.

Purpose of the Study:

  • To understand SIDS as a result of gene-environment interactions.
  • To highlight the importance of considering both genetic and environmental factors in SIDS research.

Main Methods:

  • Identification of gene polymorphisms in SIDS victims.
  • Analysis of environmental risk factors.
  • Systems biology approach to model gene-environment interactions.

Related Experiment Videos

Main Results:

  • SIDS results from the interaction of specific environmental risk factors with specific gene polymorphisms.
  • This interaction leads to phenotypes susceptible to sudden infant death.

Conclusions:

  • A comprehensive understanding of SIDS requires integrating both genetic and environmental risk factors.
  • Failure to consider this interplay will hinder research progress in SIDS.
  • Future research should focus on the complex interactions between genetics and environment in SIDS.