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Related Experiment Videos

[Mycobacterium chelonae myositis].

N Hajjaji1, B Cattier, P Lanotte

  • 1Service de réanimation médicale, CHU de Tours.

Presse Medicale (Paris, France : 1983)
|December 23, 2004
PubMed
Summary
This summary is machine-generated.

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Mycobacterium chelonae can cause rare skin and soft tissue infections, particularly in immunocompromised individuals. Early treatment with clarithromycin and ciprofloxacin is effective in resolving these rare mycobacterial infections.

Area of Science:

  • Infectious Diseases
  • Dermatology
  • Rheumatology

Background:

  • Mycobacteria rarely cause skin and soft tissue infections.
  • Mycobacterium chelonae is an environmental mycobacterium.
  • Immunocompromised status increases susceptibility to mycobacterial infections.

Observation:

  • A 49-year-old male patient with vasculitis and rheumatoid polyarthritis on long-term corticosteroid therapy developed invasive pulmonary aspergillosis.
  • The patient subsequently presented with myositis and subcutaneous abscesses in the right arm.
  • Mycobacterium chelonae was isolated from the purulent abscess material.

Findings:

  • Treatment with ciprofloxacin and clarithromycin resulted in the regression of skin and soft tissue lesions.
  • Mycobacterium chelonae infections are often resistant to antibiotics.

Related Experiment Videos

  • Clarithromycin demonstrates high efficacy against Mycobacterium chelonae.

    • Implications:

    • Corticosteroid therapy can enhance susceptibility to Mycobacterium chelonae infections.
    • Bitherapy, using clarithromycin, is recommended to prevent antibiotic resistance.
    • Prompt diagnosis and treatment are crucial for managing rare mycobacterial soft tissue infections.