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Dedifferentiated liposarcoma of the cheek
Gustavo de la Roza1, Soly Baredes, Seena C Aisner
1Department of Pathology, State University of New York-Upstate Medical University, Syracuse 13203, USA.
Annals of Diagnostic Pathology
|December 23, 2004
Summary
Dedifferentiated liposarcoma, a rare cancer, was identified in the cheek. This case highlights the importance of recognizing this rare head and neck malignancy.
Area of Science:
- Oncology
- Pathology
Background:
- Liposarcomas are rare in the head and neck, with few reported cases in the buccal mucosa.
- Dedifferentiated liposarcoma is a rare subtype, characterized by a combination of well-differentiated liposarcoma and nonlipogenic sarcoma.
Observation:
- A 61-year-old male presented with a cheek mass, initially suspected to be a salivary neoplasm.
- Initial excision revealed an atypical lipomatous tumor/well-differentiated liposarcoma.
- Recurrence 5 months later showed a predominantly nonlipogenic spindle sarcoma with rhabdomyoblastic differentiation.
Findings:
- This is the first reported case of dedifferentiated liposarcoma of the cheek.
- The recurrent tumor exhibited dedifferentiation with nonlipogenic components.
Implications:
- This case expands the known sites of dedifferentiated liposarcoma occurrence.
- Highlights the need for accurate histopathological diagnosis in head and neck soft-tissue masses.
- Underscores the aggressive nature and potential for dedifferentiation in liposarcomas.