Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Modern synthetic methods for fluorine-substituted target molecules.

Masaki Shimizu1, Tamejiro Hiyama

  • 1Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan.

Angewandte Chemie (International Ed. in English)
|December 23, 2004
PubMed
Summary

Fluorine chemistry is vital for new materials and medicines. Developing efficient synthetic methods is key to controlling fluorine

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Serum cytokine profiling reveals distinct inflammatory signatures in Kawasaki disease and MIS-C and suggests associations with coronary artery lesions.

Pediatric research·2026
Same author

Successful Treatment of Tubulointerstitial Nephritis With Uveitis Syndrome Using Adalimumab.

Pediatrics international : official journal of the Japan Pediatric Society·2026
Same author

Pericaval Fat Collection in a Patient With Systemic Juvenile Idiopathic Arthritis.

International journal of rheumatic diseases·2026
Same author

Cerebral Blood Volume Within 6 Hours of Birth in Hypoxic-Ischemic Encephalopathy Assessed Using Time-Resolved Near-Infrared Spectroscopy.

American journal of perinatology·2026
Same author

Functional characterization of Griscelli syndrome type 2 sine albinism in Japanese patients.

Journal of human immunity·2026
Same author

Case Series: Serum CXCL9 and sTNF-RII Levels as Useful Disease Activity Markers in Patients With COVID-19-Associated Multisystem Inflammatory Syndrome in Children.

International journal of rheumatic diseases·2026

Area of Science:

  • Organofluorine Chemistry
  • Materials Science
  • Medicinal Chemistry

Background:

  • Fluorine is a critical element in diverse applications, including advanced materials and biologically active compounds.
  • Synthetic fluorine chemistry advancements have enabled the creation of novel fluorinated molecules for pharmaceuticals and materials.
  • Fluorinated compounds often display unique properties due to electronic effects, posing challenges for conventional synthesis.

Purpose of the Study:

  • To address the challenges in synthesizing organofluorine compounds.
  • To promote the development of facile, efficient, and environmentally benign synthetic methods for valuable organofluorine targets.

Main Methods:

  • Exploration of synthetic strategies for organofluorine compounds.
  • Investigation into controlling the unique chemical properties of fluorinated substrates and reagents.

Related Experiment Videos

  • Focus on developing novel fluorination techniques.

    • Main Results:

    • Identification of key challenges in synthesizing fluorinated molecules.
    • Highlighting the need for specialized synthetic approaches.
    • Emphasis on the unusual reactivity of fluorinated compounds.

    Conclusions:

    • Controlling the unique properties of fluorinated compounds is crucial for advancing organofluorine chemistry.
    • Development of efficient and sustainable synthetic methods is essential for accessing valuable fluorinated molecules.
    • Further research is needed to overcome synthetic hurdles and unlock the full potential of fluorine in science and technology.