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Published on: June 11, 2009
Intestinal immunity following a single intraperitoneal immunisation in lambs
1New South Wales Department of Agriculture, Veterinary Research Station, Glenfield. NSW 2167, Australia.
Abstract:
A single intraperitoneal injection of ovalbumin in oil adjuvant in young lambs has been shown to result in the appearance in the intestinal lamina propria of antibody-containing cells, most of which contained antibody of IgA specificity. Intraperitoneal immunisation of lambs with a Salmonella typhimurium vaccine during the suckling period provided protection against postweaning challenge with live organisms. This response was shown to be associated with specific IgA antibody in intestinal secretion.
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