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[Study of stinging crystals in tian nanxing]
Yan He1, Xue-feng Feng, Jie Sun
1Inst of Chinese Materia Medica, China Academy of Tradional Chinese Medicine, 100700 Beijing, China.
Objective:
To test whether the raphides in Tian Nanxing (Pinellia pedatisecta Schott) caused irritation.
Method:
Scan Electron Microscope and Microscope Oberservation; Animal experimental study.
Result:
Through the comparision of unprocessed Tian Nanxing to processed ones which included 36 h, 72 h, 120 h processed samples, the great modifications in the structure of raphides, especially for the ones with barbs in the processed samples was observed with time course study. A further animal experimental study went to show that the rate of change for raphides with barbs existed a dose-reponse relationship to irritation.
Conclusion:
Investigations of the causes of these reactions showed that raphides of calcium oxalate are, at least in part, responsible for the Tian Nanxing's irritation.
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